Dr. Flockhart is the Harry and Edith Gladstein Chair in Cancer Genomics and Professor of Medicine, Medical Genetics and Pharmacology. He is the Director of the Division of Clinical Pharmacology at the Indiana University School of Medicine in Indianapolis, where he oversees a group now constituting 27 primary and affiliated faculty. In 2010, he became the founding director of the Indiana Institute For Personalized Medicine. His research is focused on clinically-relevant applications of pharmacogenetics and drug interactions. He is a Scot, from Edinburgh and took Honors in Biochemistry at the University of Bristol, England. He subsequently obtained a PhD from the Welsh National School of Medicine, and an MD from the University of Miami School of Medicine. He performed a residency in Internal Medicine at Georgetown University Medical Center, and after a year as Chief Medical Resident at Fairfax Hospital, completed a fellowship in Clinical Pharmacology in the Division of Clinical Pharmacology at Georgetown University Medical Center. He served on the faculty of the Georgetown Division of Clinical Pharmacology from 1993 on, and as the Director of the Pharmacogenetics Core Laboratory beginning in 1995. He has been involved in the development of new pharmacogenetic tests using array, chip and other biotechnologies, and a focus of his research is to evaluate and communicate the value of pharmacogenetic tests to physicians and pharmacists involved in clinical practice.
In 2001, he and his group moved to the Indiana University School of Medicine. He is now the Principal Investigator of the Indiana University site of the national Pharmacogenetics Research Network organized by the NIGMS and the founder and leader of COBRA, the Consortium on Breast Cancer Pharmacogenomics. Dr. Flockhart has more than 190 publications in the area of pharmacology and clinical pharmacology, in which he specializes in the study of drug interactions and the contribution of genetics to inter-individual variations in drug response. He was elected in 2010 to the American Association of Physicians. He is a member of the American Board of Clinical Pharmacology and has served on the Executive Committee and Board of the American Society for Clinical Pharmacology and Experimental Therapeutics, and as Chair of the Government Affairs Committee. Dr. Flockhart is an active teacher, and teaches the Clinical Pharmacogenetics portion of the annual course in Clinical Pharmacology at the National Institutes of Health, in Bethesda, MD and the Pharmacogenetics section of the Annual Review in Clinical Pharmacology provided by the ASCPT as well as the "Clinical Pharmacology Update" module at the Annual Meeting of the American College of Physicians. He has coordinated the bi-annual review of Clinical Pharmacology conducted by the ASCPT since 2002.