Dr. Yaoqi Alan Wang is Paige Brown Professor at the Brown Center for Immunotherapy and Department of Medicine of Indiana University and member of the Simon Comprehensive Cancer Center. Dr. Wang received his BS from SUNY Stony Brook in Biochemistry. He then completed his Ph.D training at Boston University Medical School in the field of developmental biology and his postdoctoral training in the laboratory of Philip Leder at Harvard Medical School.
Dr. Wang's recent research focus is on elucidating of the tumor microenvironment, particularly the myeloid suppressive cells by employing various orthotopic, GEM and chimeric ES tumor models. In collaboration with computational scientists, Dr. Wang has defined synthetic lethal approaches to target tumor suppressor deletion in cancers, such as deletions in PTEN, APC and SMAD4. His basic and translational work has led to a clinical trial for metastatic colon cancer.
Dr. Wang’s research is currently funded by grants from NCI and DOD. He has trained many postdoctoral fellows who have now become independent investigators at leading academic institutions. Dr. Wang will continue to collaborate with investigators on IU campus for further drug development efforts for cancer patients.