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Edward F. Srour
Robert J. and Annie S. Rohn Professor of Leukemia Research
Edward F. Srour, Ph.D., is a Professor of Medicine, Pediatrics, and Microbiology/Immunology at the Indiana University School of Medicine. Dr. Srour directs the Flow Cytometry Resource Facility of the Indiana University Cancer Center. The research program in the laboratory of Dr. Srour focuses on stem cell biology in general.
In particular, three areas of interest are pursued, hematopoietic stem cells, adult stem cells, and cancer stem cells. Investigations concerning hematopoietic stem cells examine the relationship between cell cycle status, homing and engraftment of these cells as well as the impact of the hematopoietic microenvironment through ontogeny on these properties. Using a murine model, the laboratory investigates the differentiation and lineage specification potential of a group of common pluripotent adult stem cells detected in multiple tissues and the possible utilization of these cells in tissue repair and regenerative medicine. In collaboration with other investigators at Indiana University, Dr. Srour is working on identifying cancer stem cells in breast cancer and multiple myeloma. In both areas, a major focus is determining the genetic fingerprint of cancer stem cells and in breast cancer, one of the goals of this research is to identify the relationship between putative cancer stem cells and metastasis.